Article
In vitro analysis of a constitutively active mutant form of the Escherichia coli global transcription factor FNR.
Journal of molecular biology - 27 Jan 1995
Ziegelhoffer E C, Kiley P J
Abstract excerpt
The Escherichia coli transcription factor FNR regulates expression of genes required for the metabolic switch between aerobic and anaerobic respiration. In order to investigate how FNR controls transcription of its target operons, DNA binding was examined for both the wild-type (WT) FNR protein and an altered function FNR* protein (DA154) that exhibits enhanced activity in the presence of oxygen both in vivo and...
Topics
- Bacterial Proteins
- Base Sequence
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Iron-Sulfur Proteins
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Binding