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Article

In vitro analysis of a constitutively active mutant form of the Escherichia coli global transcription factor FNR.

Journal of molecular biology - 27 Jan 1995

Ziegelhoffer E C, Kiley P J

Abstract excerpt

The Escherichia coli transcription factor FNR regulates expression of genes required for the metabolic switch between aerobic and anaerobic respiration. In order to investigate how FNR controls transcription of its target operons, DNA binding was examined for both the wild-type (WT) FNR protein and an altered function FNR* protein (DA154) that exhibits enhanced activity in the presence of oxygen both in vivo and...

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Identifiers

PMID: 7837268
DOI: 10.1006/jmbi.1994.0029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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In vitro analysis of a constitutively active mutant form of the Escherichia coli global transcription factor FNR.PMID 7837268Read ↗

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Characterization of FNR* mutant proteins indicates two distinct mechanisms for altering oxygen regulation of the Escherichia coli transcription factor FNR.Semantic proximity Read ↗

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DNA binding and dimerization of the Fe-S-containing FNR protein from Escherichia coli are regulated by oxygen.Semantic proximity Read ↗

In vivo and in vitro mutants of FNR the anaerobic transcriptional regulator of E. coli.Semantic proximity Read ↗

Transcription activation by Escherichia coli FNR protein: similarities to, and differences from, the CRP paradigm.Semantic proximity Read ↗

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A new glimpse of FadR-DNA crosstalk revealed by deep dissection of the E. coli FadR regulatory protein.Semantic proximity Read ↗

Regulation of aerobic-to-anaerobic transitions by the FNR cycle in Escherichia coli.Semantic proximity Read ↗

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Characterization of the fatty acid-responsive transcription factor FadR. Biochemical and genetic analyses of the native conformation and functional domains.Semantic proximity Read ↗

A reassessment of the FNR regulon and transcriptomic analysis of the effects of nitrate, nitrite, NarXL, and NarQP as Escherichia coli K12 adapts from aerobic to anaerobic growth.Semantic proximity Read ↗

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