Article
Immunization against tumor and minor histocompatibility antigens by eluted cellular peptides loaded on antigen processing defective cells.
European journal of immunology - 1 Oct 1993
Franksson L, Petersson M, Kiessling R, Kärre K
Abstract excerpt
Material eluted from RMA lymphoma or B6 spleen cells under acid conditions was fractionated by reverse phase high-performance liquid chromatography, and tested for ability to restore the sensitivity to cytotoxic T lymphocytes of the processing/presentation defective mutant line RMA-S. This allowed identification of three fractions (termed M1, M2 and M3) carrying B6 antigens recognized by cytotoxic T lymphocytes...
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