Article
Dissection of H-2Db-restricted cytotoxic T-lymphocyte epitopes on simian virus 40 T antigen by the use of synthetic peptides and H-2Dbm mutants.
Journal of virology - 1 Mar 1990
Tevethia S S, Lewis M, Tanaka Y, Milici J, Knowles B, Maloy W L, Anderson R
Abstract excerpt
Five distinct cytotoxic T-lymphocyte (CTL) recognition sites were identified in the simian virus 40 (SV40) T antigen by using H-2b cells that express the truncated T antigen or antigens carrying internal deletions of various sizes. Four of the CTL recognition determinants, designated sites I, II,...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Polyomavirus Transforming
- Cell Line
- Clone Cells
- Epitopes
- Genes, MHC Class I
- H-2 Antigens
- Histocompatibility Antigen H-2D
- Mice
- Mice, Inbred C57BL
- Molecular Sequence Data
- Mutation
- Peptide Mapping
- Peptides