Article
Differential recruitment of viral and allo-epitopes into the MHC class I antigen processing pathway of a novel mutant of Ltk- cells. HSV/MHC class I restriction/immune recognition/antigen processing/antigen presentation/influenza virus.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1993
Lippé R, Kolaitis G, Michaelis C, Tufaro F, Jefferies W A
Abstract excerpt
It is generally thought that the Ag processing pathways for endogenously synthesized proteins are the same for allo and viral Ag processing. However, this view does not take into consideration the diversity of specialized maturation and assembly pathways for viruses. In particular, viral assembly that takes place within intracellular membranes may require unique Ag processing steps. In this study we sought to...
Topics
- Animals
- Antigen-Presenting Cells
- Antigens, Viral
- Cell Line
- Chemokine CXCL1
- Chemokines, CXC
- Chemotactic Factors
- Epitopes
- Growth Substances
- H-2 Antigens