Article
A human minor histocompatibility antigen which appears to segregate with the major histocompatibility complex.
Transplantation - 15 Aug 1994
Vinci G, Masset M, Semana G, Vernant J P
Abstract excerpt
We obtained a cell line (So1) from a patient who rejected a T-depleted allogeneic BMT. Cytotoxic activity by cell-mediated lympholysis was found using So1 as effector and EBV-transformed donor B cells as targets, but no lysis of the patient's pretransplantation cells and of an unrelated HLA-nonidentical subject was observed, suggesting it was related to recognition of a minor transplantation antigen which could...
Topics
- Adult
- Bone Marrow Transplantation
- Cell Line
- Cytotoxicity, Immunologic
- Electrophoresis, Polyacrylamide Gel
- Female
- Graft Rejection
- Histocompatibility Testing
- Humans
- Major Histocompatibility Complex
- Male
