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Article

A new yeast translation initiation factor suppresses a mutation in the eIF-4A RNA helicase.

The EMBO journal - 1 Oct 1993

Coppolecchia R, Buser P, Stotz A, Linder P

Abstract excerpt

We have isolated a gene, STM1, which encodes a new translation initiation factor from Saccharomyces cerevisiae. The gene acts, if present on a multicopy plasmid, as a suppressor of a temperature-sensitive mutation in eIF-4A. The single copy STM1 gene is not essential, but disruption causes a slow growth phenotype. Analysis of polysomes from a strain carrying a disrupted stm1 allele shows a clear defect in...

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Identifiers

PMID: 8404866
DOI: 10.1002/j.1460-2075.1993.tb06078.x
PMCID: PMC413683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A new yeast translation initiation factor suppresses a mutation in the eIF-4A RNA helicase.PMID 8404866Read ↗

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