Article
Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae.
The EMBO journal - 16 Feb 1998
de la Cruz J, Kressler D, Tollervey D, Linder P
Abstract excerpt
The temperature-sensitive mutation, dob1-1, was identified in a screen for dependence on overexpression of the yeast translation initiation factor eIF4B (Tif3p). Dob1p is an essential putative ATP-dependent RNA helicase. Polysome analyses revealed an under accumulation of 60S ribosomal subunits i...
Topics
- Cloning, Molecular
- DEAD-box RNA Helicases
- Eukaryotic Initiation Factors
- Exoribonucleases
- Fungal Proteins
- Galactose
- Mutagenesis
- Nuclear Proteins
- Peptide Initiation Factors
- Phenotype
- RNA Helicases
- RNA Nucleotidyltransferases
- RNA Precursors
- RNA Processing, Post-Transcriptional
- RNA, Ribosomal, 5S
- RNA-Binding Proteins
- Ribosomal Proteins
- Saccharomyces cerevisiae