Article
Allelic-expression imbalance of the insulin-like growth factor 2 gene in hepatocellular carcinoma and underlying disease.
Oncogene - 4 Apr 1996
Takeda S, Kondo M, Kumada T, Koshikawa T, Ueda R, Nishio M, Osada H, Suzuki H, Nagatake M, Washimi O, Takagi K, Takahashi T, Nakao A, Takahashi T
Abstract excerpt
It has been well documented that the liver is an exceptional organ in which the monoallelic expression of insulin-like growth factor 2 (IGF2) due to genomic imprinting is relaxed during the postnatal period, resulting in biallelic expression thereafter. In the present study, changes in the status...
Topics
- Alleles
- Base Sequence
- Carcinoma, Hepatocellular
- Chronic Disease
- DNA Primers
- Genomic Imprinting
- Hepatitis B
- Hepatitis C
- Humans
- Insulin-Like Growth Factor II
- Liver Cirrhosis
- Liver Neoplasms
- Molecular Sequence Data