Article
Expression of p53 gene in 184 unifocal hepatocellular carcinomas: association with tumor growth and invasiveness.
Cancer research - 1 Oct 1993
Hsu H C, Tseng H J, Lai P L, Lee P H, Peng S Y
Abstract excerpt
To elucidate the biological significance of the p53 gene expression in human hepatocellular carcinoma (HCC), the p53 protein was studied in 184 resected unifocal primary HCCs, including 102 small (< or = 5 cm) and 82 large HCCs (> 5 cm), using immunocytochemistry. The p53 mRNA expression was anal...
Topics
- Blotting, Northern
- Carcinoma, Hepatocellular
- Cell Division
- DNA, Neoplasm
- Gene Expression
- Genes, p53
- Humans
- Immunohistochemistry
- Liver Neoplasms
- Mutation
- Neoplasm Invasiveness
- Polymerase Chain Reaction