Article
Overexpression of p53: a rare event in a large series of white patients with hepatocellular carcinoma.
Hepatology (Baltimore, Md.) - 1 Nov 1992
Laurent-Puig P, Flejou J F, Fabre M, Bedossa P, Belghiti J, Gayral F, Franco D
Abstract excerpt
Mutant p53 has been found in a wide variety of human malignancies including carcinomas of the lung, breast and colon. Because of the controversial mutational rate of the p53 gene in hepatocellular carcinoma, a large series of liver tumors from white patients with different risk factors was examined immunohistochemically for expression of the p53 mutant to assess its prevalence and the relationships between p53...
Topics
- Adult
- Aged
- Antibodies, Monoclonal
- Carcinoma, Hepatocellular
- Female
- Hepacivirus
- Hepatitis Antibodies
- Humans
- Immunoenzyme Techniques
- Liver Neoplasms
- Male