Article
Overexpression of p53 in a large series of patients with hepatocellular carcinoma: a clinicopathological correlation.
Anticancer research - 1 Jan 2000
Caruso M L, Valentini A M
Abstract excerpt
p53 mutant protein has been found in a variety of human malignancies. In order to assess the controversial role of p53 protein in hepatocellular carcinoma (HCC) we studied its immunohistochemical expression in a series of 193 HCC specimens. Positive immunostaining for p53 was detected in the nuclei of neoplastic cells of 29 (15%) HCCs. There was no immunohistochemical evidence of mutant p53 expression either in...
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