Article
P53 immunohistochemical scoring: an independent prognostic marker for patients after hepatocellular carcinoma resection.
World journal of gastroenterology - 1 Jun 2002
Qin Lun-Xiu, Tang Zhao-You, Ma Zeng-Chen, Wu Zhi-Quan, Zhou Xin-Da, Ye Qing-Hai, Ji Yuan, Huang Li-Wen, Jia Hu-Liang, Sun Hui-Chuan, Wang Lu
Abstract excerpt
AIM: To confirm if p53 mutation could be a routine predictive marker for the prognosis of hepatocellular carcinoma (HCC) patients. METHODS: Two hundreds and forty-four formalin-fixed paraffin-embedded tumor samples of the patients with HCC receiving liver resection were detected for nuclear accumulation of p53. The percent of P53 immunoreactive tumor cells was scored as 0 to 3+ in P53 positive region (<10% -,...
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