The Long-To-Short-Axis Ratio and Multifocality are Associated With TP53 Mutation Status in Surgically Resected Hepatocellular Carcinomas.

doi:10.1016/j.acra.2018.04.021

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Article

The Long-To-Short-Axis Ratio and Multifocality are Associated With TP53 Mutation Status in Surgically Resected Hepatocellular Carcinomas.

Academic radiology - 1 Dec 2020

Wang Xiaodong, Chen Dongying, Chen Bin

Abstract excerpt

RATIONALE AND OBJECTIVES: In hepatocellular carcinoma (HCC), the tumor protein 53 (TP53) gene is frequently mutated and the mutations have been associated with poor prognosis. We aim to retrospectively identify the relationship between TP53 mutation status, tumor size (long-axis diameter, short-axis diameter, and long-to-short-axis ratio [L/S ratio]), margin and multifocality in surgically resected HCC. MATERIALS...

Topics

Carcinoma, Hepatocellular
Humans
Liver Neoplasms
Mutation
Prognosis
Retrospective Studies
Tumor Suppressor Protein p53

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Open in PubMed

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PMID: 29941397
DOI: 10.1016/j.acra.2018.04.021

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