Article
p73 overexpression and nuclear accumulation in hepatitis C virus-associated hepatocellular carcinoma.
Digestive diseases and sciences - 1 Apr 2002
Zemel Romy, Koren Claud, Bachmatove Larisa, Avigad Smadar, Kaganovsky Ella, Okon Elimelech, Ben-Ari Ziv, Grief Franklin, Ben-Yehoyada Merav, Shaul Yosef, Tur-Kaspa Ran
Abstract excerpt
p73 is the first identified homolog of p53, but its function has not been established. Our study investigated the expression of p73 in liver tissue of patients with hepatitis C virus (HCV)-associated hepatocellular carcinoma (HCC). RT-PCR was performed on RNA extracted from tumorous and nontumorous liver tissue of HCV-associated HCC, and control tissue and the cDNA were sequenced. Anti-p73 polyclonal antibodies...
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