Article
DNA typing for HLA-DPB1-alleles in German patients with systemic lupus erythematosus using the polymerase chain reaction and DIG-ddUTP-labelled oligonucleotide probes. Members of SLE Study Group.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1993
Yao Z, Hartung K, Deicher H G, Brünnler G, Bettinotti M P, Keller E, Paul C, Gawron C, Mikschl S, Albert E
Abstract excerpt
Genomic DNA of 178 German Caucasian patients with systemic lupus erythematosus are studied for HLA-DP locus by using PCR and DIG-ddUTP-labelled oligonucleotide probes. A significant increase of DPB1*0101 is observed in SLE patients compared with healthy controls (chi 2 = 15.27, p.c. < 0.004). DPB1*0501 and *0901 are also slightly increased (chi 2 = 5.85, P < 0.05, p.c. = NS; chi 2 = 5.64, P < 0.05, p.c. = NS)....
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