Article
DNA typing for HLA-DPB1-alleles in German patients with systemic lupus erythematosus using the polymerase chain reaction and DIG-ddUTP-labelled oligonucleotide probes. Members of SLE Study Group.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1993
Yao Z, Hartung K, Deicher H G, Brünnler G, Bettinotti M P, Keller E, Paul C, Gawron C, Mikschl S, Albert E
Abstract excerpt
Genomic DNA of 178 German Caucasian patients with systemic lupus erythematosus are studied for HLA-DP locus by using PCR and DIG-ddUTP-labelled oligonucleotide probes. A significant increase of DPB1*0101 is observed in SLE patients compared with healthy controls (chi 2 = 15.27, p.c. < 0.004). DPB...
Topics
- Alleles
- Base Sequence
- DNA
- Female
- Gene Frequency
- Germany
- HLA-DP Antigens
- HLA-DP beta-Chains
- Humans
- Lupus Erythematosus, Systemic
- Male
- Molecular Sequence Data
- Oligonucleotide Probes