Article
HLA-DP genotyping in patients with systemic lupus erythematosus: correlations with autoantibody subsets.
The Journal of rheumatology - 1 Jan 1992
Galeazzi M, Sebastiani G D, Passiu G, Angelini G, Delfino L, Asherson R A, Khamashta M A, Hughes G R
Abstract excerpt
In order to ascertain whether the HLA-DP locus plays a role in the genetic predisposition for systemic lupus erythematosus (SLE), 42 patients with SLE were typed for 17 different DPBeta haplotypes by locus specific amplification followed by allele specific oligonucleotide hybridization. Sera from...
Topics
- Adult
- Alleles
- Autoantibodies
- Female
- Gene Frequency
- Genotype
- HLA-DP Antigens
- Humans
- Lupus Erythematosus, Systemic
- Male