Article
Gene polymorphism of HLA-DPB1 and DPA1 loci in caucasoid population: frequencies and DPB1-DPA1 associations.
Human immunology - 1 Aug 1991
al-Daccak R, Wang F Q, Theophille D, Lethielleux P, Colombani J, Loiseau P
Abstract excerpt
The genetic polymorphism of the HLA-DPB1 and DPA1 loci was studied in 60 unrelated caucasoid individuals by PCR-RFLP. The polymorphic second exon of DPB1, the third exon of DPA1, and the transmembrane DPA1 exon were specifically amplified in vitro by polymerase chain reaction (PCR). Amplified DNA...
Topics
- Alleles
- Base Sequence
- Chromosome Mapping
- Electrophoresis, Agar Gel
- Exons
- Gene Frequency
- HLA-DP Antigens
- Humans
- Molecular Sequence Data
- Oligonucleotide Probes
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Random Allocation
- White People
