Article
Polymorphism of HLA-DMA and DMB alleles in patients with systemic lupus erythematosus.
The Journal of rheumatology - 1 Jul 2003
Morel Jacques, Simoes Clarisse Da Silva, Avinens Odile, Sany Jacques, Combe Bernard, Eliaou Jean-Francois
Abstract excerpt
OBJECTIVE: To evaluate the contribution of HLA-DM alleles to susceptibility to systemic lupus erythematosus (SLE) in a Caucasian population. METHODS: HLA-DMA and DMB alleles were studied in 73 patients with SLE, 147 randomly selected controls, and 86 HLA-DRB1 genotype matched controls by oligotyping of polymerase chain reaction amplified genomic DNA with sequence-specific oligonucleotide probes. RESULTS: There...
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