Article
No direct correlation between HLA-DPB1 and antibodies against recombinant Ro (SS-A)/La (SS-B) proteins in systemic lupus erythematosus. SLE Study Group.
Rheumatology international - 1 Jan 1993
Yao Z, Hartung K, Ehrfeld H, Seelig H P, Deicher H G, Brünnler G, Keller E, Albert E
Abstract excerpt
We investigated the association of HLA-DPB1 alleles with the occurrence of autoantibodies against Ro (SS-A) or La (SS-B) using recombinant 52 kD-Ro, 60 kD-Ro and La proteins in 177 German patients with systemic lupus erythematosus (SLE). A significant increase in the frequency of DPB1*0101 is obs...
Topics
- Alleles
- Antibodies, Antinuclear
- Autoantibodies
- Enzyme-Linked Immunosorbent Assay
- Genetic Linkage
- Germany
- HLA-DP Antigens
- HLA-DP beta-Chains
- Haplotypes
- Humans
- Lupus Erythematosus, Systemic
- Multicenter Studies as Topic
- Recombinant Proteins
