Article
HLA-DPB1 oligonucleotide typing of a southwest German Caucasian population.
Tissue antigens - 1 Nov 1991
Eiermann T H, Fakler J, Müller C R, Ballas M, Goldmann S F
Abstract excerpt
HLA-DP genotyping with sequence-specific oligonucleotides can detected known sequence variations in the polymorphic segments of the DPB1 second exon. Since the allelic polymorphism of the 22 published alleles is based on recombination of sequence motifs from six variable regions, DPB1 typing depends on the reactivity pattern of many different probes rather than from typing with single allele-specific probes. By...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- DNA
- Gene Frequency
- Genotype
- Germany
- HLA-DP Antigens
- HLA-DP beta-Chains
- Humans
- Molecular Sequence Data
- Nucleic Acid Hybridization