Article
HLA-DPB1 alleles association of anticardiolipin and anti-beta2GPI antibodies in a large series of European patients with systemic lupus erythematosus.
Lupus - 1 Jan 2003
Sebastiani G D, Galeazzi M, Tincani A, Scorza R, Mathieu A, Passiu G, Morozzi G, Piette J C, Cervera R, Houssiau F, Smolen J, Fernandez Nebro A, De Ramon E, Goral A Jedryka, Papasteriades C, Ferrara G B, Carcassi C, Bellisai F, Marcolongo R
Abstract excerpt
Our objective was to determine the HLA-DPB1 allele associations of anticardiolipin (aCL) and anti-beta2GPI (a(beta)2GPI) antibodies, and of clinical manifestations of the antiphospholipid syndrome (APS), in systemic lupus erythematosus (SLE). We studied 577 European patients with SLE. aCL and a(beta)2GPI antibodies were measured by ELISA. Molecular typing of HLA-DPB1 locus was performed by polymerase chain...
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