Article
DNA typing for HLA-DR, and -DP alleles in a Chinese population using the polymerase chain reaction (PCR) and oligonucleotide probes.
Tissue antigens - 1 Jul 1991
Gao X J, Sun Y P, An J B, Fernandez-Viña M, Qou J N, Lin L, Stastny P
Abstract excerpt
We have determined alleles of HLA-DRB1, DRB3, DRB5, DQA1, DQB1, and DPB1 loci in 91 unrelated healthy individuals from North China. Group-specific PCR primers were employed for the analysis of subsets of DR1, DR2, DR4, DRw52, and DPB. With allele-specific probes, 22 DRB1, 8 DQA1, 13 DQB1, and 12 DPB1 alleles were found in this panel. Allele frequencies showed that 25.3% of the subjects had DR7 and 26.4% had DR9,...
Topics
- Alleles
- Asian People
- China
- DNA
- Gene Frequency
- HLA-DP Antigens
- HLA-DR Antigens
- Humans
- Linkage Disequilibrium
- Oligonucleotide Probes
- Polymerase Chain Reaction
