Article
Mutational and functional analysis of dominant SPT2 (SIN1) suppressor alleles in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Sept 1993
Lefebvre L, Smith M
Abstract excerpt
The Saccharomyces cerevisiae SPT2 gene was identified by genetic screens for mutations which are suppressors of Ty and delta insertional mutations at the HIS4 locus. The ability of spt2 mutations to suppress the transcriptional interference caused by the delta promoter insertion his-4-912 delta c...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Chromosomal Proteins, Non-Histone
- DNA Mutational Analysis
- DNA Transposable Elements
- DNA-Binding Proteins
- Gene Expression Regulation, Fungal
- Genes, Dominant
- Genes, Fungal
- Genes, Suppressor
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Deletion
- Structure-Activity Relationship
- Transcription, Genetic