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Article

Analysis of a mutant histone H3 that perturbs the association of Swi/Snf with chromatin.

Molecular and cellular biology - 1 Jan 2004

Duina Andrea A, Winston Fred

Abstract excerpt

We have isolated new histone H3 mutants in Saccharomyces cerevisiae that confer phenotypes indicative of transcriptional defects. Here we describe the characterization of one such mutant, encoded by the hht2-11 allele, which contains the single amino acid change L61W in the globular domain of H3. Whole-genome expression analyses show that the hht2-11 mutation confers pleiotropic transcriptional defects and that...

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Identifiers

PMID: 14701730
DOI: 10.1128/MCB.24.2.561-572.2004
PMCID: PMC343804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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