Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear proteins Nut1p and Nut2p cooperate to negatively regulate a Swi4p-dependent lacZ reporter gene in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Aug 1998

Tabtiang R K, Herskowitz I

Abstract excerpt

The URS2 region of the Saccharomyces cerevisiae HO upstream region contains 10 binding sites for the Swi4p/Swi6p transcription factor and confers Swi4p dependence for transcription. Using a hybrid promoter, UASGAL (upstream activation sequence of GAL1)-URS2R, in which the GAL1-10 regulatory region is fused to the proximal 360 bp of URS2, we isolated mutants in which Swi4p is no longer required for transcription....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fungal Proteins

Share to Molecular Sequence Data

Share to Mutagenesis

Share to Nuclear Proteins

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 9671481
DOI: 10.1128/MCB.18.8.4707
PMCID: PMC109057

Genes

CCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nuclear proteins Nut1p and Nut2p cooperate to negatively regulate a Swi4p-dependent lacZ reporter gene in Saccharomyces cerevisiae.PMID 9671481Read ↗

A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1.Semantic proximity Read ↗

DEAD-box RNA helicase Sub2 is required for expression of lacZ fusions in Saccharomyces cerevisiae and is a dosage-dependent suppressor of RLR1 (THO2).Semantic proximity Read ↗

SIN1 interacts with a protein that binds the URS1 region of the yeast HO gene.Semantic proximity Read ↗

Genetic analysis of the YDR1-BUR6 repressor complex reveals an intricate balance among transcriptional regulatory proteins in yeast.Semantic proximity Read ↗

Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription.Semantic proximity Read ↗

Epistasis analysis of suppressor mutations that allow HO expression in the absence of the yeast SW15 transcriptional activator.Semantic proximity Read ↗

The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres.Semantic proximity Read ↗

Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells.Semantic proximity Read ↗

Members of the RSC chromatin-remodeling complex are required for maintaining proper nuclear envelope structure and pore complex localization.Semantic proximity Read ↗

RLR1 (THO2), required for expressing lacZ fusions in yeast, is conserved from yeast to humans and is a suppressor of SIN4.Semantic proximity Read ↗

Antagonistic remodelling by Swi-Snf and Tup1-Ssn6 of an extensive chromatin region forms the background for FLO1 gene regulation.Semantic proximity Read ↗

Suppressor mutations that make the essential transcription factor Spn1/Iws1 dispensable in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.