Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DNA-binding domain of the yeast Spt10p activator includes a zinc finger that is homologous to foamy virus integrase.

The Journal of biological chemistry - 17 Mar 2006

Mendiratta Geetu, Eriksson Peter R, Shen Chang-Hui, Clark David J

Abstract excerpt

The yeast SPT10 gene encodes a putative histone acetyltransferase that binds specifically to pairs of upstream activating sequence (UAS) elements found only in the histone gene promoters. Here, we demonstrate that the DNA-binding domain of Spt10p is located between residues 283 and 396 and includes a His(2)-Cys(2) zinc finger. The binding of Spt10p to the histone UAS is zinc-dependent and is disabled by a zinc...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histone Acetyltransferases

Share to Histones

Share to Integrases

Share to Oligonucleotide Array Sequence Analysis

Share to Zinc Fingers

Source

Identifiers

PMID: 16415340
DOI: 10.1074/jbc.M511416200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DNA-binding domain of the yeast Spt10p activator includes a zinc finger that is homologous to foamy virus integrase.PMID 16415340Read ↗

Global regulation by the yeast Spt10 protein is mediated through chromatin structure and the histone upstream activating sequence elements.Semantic proximity Read ↗

Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae.Semantic proximity Read ↗

Spt10-dependent transcriptional activation in Saccharomyces cerevisiae requires both the Spt10 acetyltransferase domain and Spt21.Semantic proximity Read ↗

SPT5, an essential gene important for normal transcription in Saccharomyces cerevisiae, encodes an acidic nuclear protein with a carboxy-terminal repeat.Semantic proximity Read ↗

The Saccharomyces cerevisiae SPT7 gene encodes a very acidic protein important for transcription in vivo.Semantic proximity Read ↗

Mutations in the SPT4, SPT5, and SPT6 genes alter transcription of a subset of histone genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

Evidence that Spt6p controls chromatin structure by a direct interaction with histones.Semantic proximity Read ↗

Transcription elongation factors repress transcription initiation from cryptic sites.Semantic proximity Read ↗

Control of chromatin structure by spt6: different consequences in coding and regulatory regions.Semantic proximity Read ↗

A conserved genetic interaction between Spt6 and Set2 regulates H3K36 methylation.Semantic proximity Read ↗

Analysis of transcriptional activation at a distance in Saccharomyces cerevisiae.Semantic proximity Read ↗

SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.