Mutations in the SPT4, SPT5, and SPT6 genes alter transcription of a subset of histone genes in Saccharomyces cerevisiae.

doi:10.1093/genetics/143.4.1543

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Article

Mutations in the SPT4, SPT5, and SPT6 genes alter transcription of a subset of histone genes in Saccharomyces cerevisiae.

Genetics - 1 Aug 1996

Compagnone-Post P A, Osley M A

Abstract excerpt

The SPT4, SPT5, and SPT6 gene products define a class of transcriptional repressors in Saccharomyces cerevisiae that are thought to function through their effects on chromatin assembly or stability. Mutations in these genes confer a similar range of phenotypes to mutations in HIR genes, which enc...

Topics

Chromosomal Proteins, Non-Histone
Feedback
Fungal Proteins
Genes, Fungal
Genes, Reporter
Histone Chaperones
Histones
Lac Operon
Mutation
Nuclear Proteins
Phenotype
Repressor Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Transcription, Genetic
Transcriptional Elongation Factors

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Identifiers

PMID: 8844144
DOI: 10.1093/genetics/143.4.1543
PMCID: PMC1207419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8844144-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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