Article
Antigen processing mutant T2 cells present viral antigen restricted through H-2Kb.
European journal of immunology - 1 Aug 1993
Zhou X, Glas R, Liu T, Ljunggren H G, Jondal M
Abstract excerpt
Cytotoxic T lymphocytes (CTL) recognize foreign antigens as short peptides presented by class I molecules of the major histocompatibility complex (MHC). T2 cells are profoundly defective in the presentation of endogenously synthesized antigens to CTL due to a deletion of MHC class II-encoded gene...
Topics
- Animals
- Antigen-Presenting Cells
- Antigens, Viral
- Brefeldin A
- Cell Line
- Cyclopentanes
- Female
- H-2 Antigens
- Mice
- Mice, Inbred C57BL
- Mutation
- Orthomyxoviridae
- Parainfluenza Virus 1, Human
- T-Lymphocytes, Cytotoxic
- Vesicular stomatitis Indiana virus