Article
Characterization of virulence genes of enteroinvasive Escherichia coli by TnphoA mutagenesis: identification of invX, a gene required for entry into HEp-2 cells.
Journal of bacteriology - 1 Aug 1993
Hsia R C, Small P L, Bavoil P M
Abstract excerpt
While enteroinvasive Escherichia coli (EIEC) and shigellae are genotypically nearly identical, a difference has been reported in the infective dose to humans: EIEC is 10,000-fold less infectious than shigellae. A possible basis for this difference lies in the inherent invasiveness of these bacter...
Topics
- Amino Acid Sequence
- Base Sequence
- Cells, Cultured
- Cloning, Molecular
- DNA Transposable Elements
- Escherichia coli
- Gene Expression
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Phenotype
- Plasmids
- Shigella flexneri
- Transcription, Genetic
- Virulence