Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of two Shigella flexneri chromosomal loci involved in intercellular spreading.

Infection and immunity - 1 Oct 1998

Hong M, Gleason Y, Wyckoff E E, Payne S M

Abstract excerpt

The ability of Shigella flexneri to multiply within colonic epithelial cells and spread to adjacent cells is essential for production of dysentery. Two S. flexneri chromosomal loci that are required for these processes were identified by screening a pool of TnphoA insertion mutants. These mutants were able to invade cultured epithelial cells but could not form wild-type plaques. Analysis of the nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Cells, Cultured
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Bacterial

Share to Membrane Proteins

Share to Molecular Sequence Data

Share to Phenotype

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 9746567
DOI: 10.1128/IAI.66.10.4700-4710.1998
PMCID: PMC108578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of two Shigella flexneri chromosomal loci involved in intercellular spreading.PMID 9746567Read ↗

Identification and characterization of ispA, a Shigella flexneri chromosomal gene essential for normal in vivo cell division and intracellular spreading.Semantic proximity Read ↗

Virulence-associated chromosomal loci of Shigella flexneri identified by random Tn5 insertion mutagenesis.Semantic proximity Read ↗

Genetic and Molecular Basis of Epithelial Cell Invasion by Shigella SpeciesSemantic proximity Read ↗

A translocation-competent pore is required for <i>Shigella flexneri</i> to escape from the double membrane vacuole during intercellular spreadSemantic proximity Read ↗

<i>Shigella flexneri</i> disruption of host cell-cell tension promotes intercellular spreadSemantic proximity Read ↗

Outer membrane protein A (OmpA): a new player in shigella flexneri protrusion formation and inter-cellular spreading.Semantic proximity Read ↗

A system for identifying post-invasion functions of invasion genes: requirements for the Mxi-Spa type III secretion pathway of Shigella flexneri in intercellular dissemination.Semantic proximity Read ↗

Disruption of IcsP, the major Shigella protease that cleaves IcsA, accelerates actin-based motility.Semantic proximity Read ↗

Gastrointestinal signals in supplemented media reveal a role in adherence for the Shigella flexneri sap autotransporter gene.Semantic proximity Read ↗

vacC, a virulence-associated chromosomal locus of Shigella flexneri, is homologous to tgt, a gene encoding tRNA-guanine transglycosylase (Tgt) of Escherichia coli K-12.Semantic proximity Read ↗

Identification and characterization of a chromosomal virulence gene, <i>vacJ</i>, required for intercellular spreading of <i>Shigella flexneri</i>Semantic proximity Read ↗

Identification and characterization of virK, a virulence-associated large plasmid gene essential for intercellular spreading of Shigella flexneri.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.