Article
Identification of two Shigella flexneri chromosomal loci involved in intercellular spreading.
Infection and immunity - 1 Oct 1998
Hong M, Gleason Y, Wyckoff E E, Payne S M
Abstract excerpt
The ability of Shigella flexneri to multiply within colonic epithelial cells and spread to adjacent cells is essential for production of dysentery. Two S. flexneri chromosomal loci that are required for these processes were identified by screening a pool of TnphoA insertion mutants. These mutants...
Topics
- Bacterial Proteins
- Cell Membrane Permeability
- Cells, Cultured
- Chromosomes, Bacterial
- Cloning, Molecular
- Congo Red
- Deoxycholic Acid
- Genes, Bacterial
- Genetic Complementation Test
- Hemin
- Loop of Henle
- Membrane Proteins
- Molecular Sequence Data
- Mutagenesis, Insertional
- Operon
- Phenotype
- Sequence Analysis, DNA
- Shigella flexneri