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Article

Separable regulatory elements governing myogenin transcription in mouse embryogenesis.

Science (New York, N.Y.) - 9 Jul 1993

Cheng T C, Wallace M C, Merlie J P, Olson E N

Abstract excerpt

Expression of the myogenic helix-loop-helix (HLH) protein myogenin in muscle cell precursors within somites and limb buds is among the earliest events associated with myogenic lineage determination in vertebrates. Mutations in the myogenin promoter that abolish binding sites for myogenic HLH proteins or myocyte enhancer factor-2 (MEF-2) suppressed transcription of a linked lacZ transgene in subsets of myogenic...

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Source

Identifiers

PMID: 8392225
DOI: 10.1126/science.8392225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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