Article
Emergence and selection of RNA virus variants: memory and extinction.
Virus research - 30 Jan 2002
Domingo Esteban, Ruiz-Jarabo Carmen M, Sierra Saleta, Arias Armando, Pariente Nonia, Baranowski Eric, Escarmis Cristina
Abstract excerpt
Two features of viral quasispecies are reviewed: the presence of memory genomes as minority components of their mutant spectra, and viral extinction due to enhanced mutagenesis. Memory has been documented with several genetic markers of the important animal picornavirus foot-and-mouth disease virus (FMDV). The presence of memory genomes in viral quasispecies may accelerate their adaptive response whenever a...
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