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Article

Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism

1 Jun 1993

Abstract excerpt

The human hepatitis C virus (HCV) contains a long 5' noncoding region (5' NCR). Computer-assisted and biochemical analyses suggest that there is a complex secondary structure in this region that is comparable to the secondary structures that are found in picornaviruses (E.A. Brown, H. Zhang, L.-H. Ping, and S.M. Lemon, Nucleic Acids Res. 20:5041-5045, 1992). Previous in vitro studies suggest that the HCV 5' NCR...

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Identifiers

PMID: 8388503
DOI: 10.1128/jvi.67.6.3338-3344.1993

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