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Article

Involvement of the 5' proximal coding sequences of hepatitis C virus with internal initiation of viral translation.

Biochemical and biophysical research communications - 18 Nov 1998

Hwang L H, Hsieh C L, Yen A, Chung Y L, Chen D S

Abstract excerpt

The 5' nontranslated region (NTR) of hepatitis C virus (HCV) consists of 341 nucleotides (nt). This region comprises the majority of the internal ribosome entry site (IRES) which controls the efficiency of viral translation. Previous studies of the 3' boundary of the HCV IRES yielded conflicting data regarding the involvement of viral coding sequences in IRES activity. We therefore studied the functional...

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Identifiers

PMID: 9826551
DOI: 10.1006/bbrc.1998.9673

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CAT

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Involvement of the 5' proximal coding sequences of hepatitis C virus with internal initiation of viral translation.PMID 9826551Read ↗

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