Article
Role of the cyclic AMP response element in rat fibronectin gene expression.
Hepatology (Baltimore, Md.) - 1 May 1993
Miao S, Suri P K, Shu-Ling L, Abraham A, Cook N, Milos P, Zern M A
Abstract excerpt
Fibronectin expression is of considerable importance in normal and fibrotic liver. Plasma fibronectin levels are correlated with good prognosis in liver failure, and cellular fibronectin plays a crucial role in fibrogenesis. In this study, we observed that the H4II rat hepatoma cell line does not express fibronectin. Furthermore, a recombinant vector (pFGH) containing the promoter elements of the fibronectin gene...
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