Article
One of three CCArGG box/serum response elements of the beta-actin gene is an insulin-responsive element.
Endocrinology - 1 Jan 1995
Onyia J E, Halladay D L, Messina J L
Abstract excerpt
The cytoskeletal actins are abundant proteins in mammalian nonmuscle cells. We have previously reported that physiological concentrations of insulin induced beta-actin transcription in rat H4 hepatoma cells. To define whether one or more of the three CCArGG box elements or other elements within the beta-actin gene promoter is an insulin response element, we transfected H4 cells with regions of the human...
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