One of three CCArGG box/serum response elements of the beta-actin gene is an insulin-responsive element.

doi:10.1210/endo.136.1.7828546

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Article

One of three CCArGG box/serum response elements of the beta-actin gene is an insulin-responsive element.

Endocrinology - 1 Jan 1995

Onyia J E, Halladay D L, Messina J L

Abstract excerpt

The cytoskeletal actins are abundant proteins in mammalian nonmuscle cells. We have previously reported that physiological concentrations of insulin induced beta-actin transcription in rat H4 hepatoma cells. To define whether one or more of the three CCArGG box elements or other elements within t...

Topics

Actins
Animals
Base Sequence
Blood Physiological Phenomena
DNA
Gene Deletion
Gene Expression
Genes
Insulin
Molecular Probes
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Rats
Regulatory Sequences, Nucleic Acid
Tumor Cells, Cultured

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