Article
G10BP, an E1A-inducible negative regulator of Sp1, represses transcription of the rat fibronectin gene.
Molecular and cellular biology - 1 Oct 1995
Suzuki M, Kuroda C, Oda E, Tsunoda S, Nakamura T, Nakajima T, Oda K
Abstract excerpt
Downregulation of the fibronectin (FN) gene in a rat 3Y1 derivative cell line, XhoC, transformed by the adenovirus E1A and E1B genes seems to be caused by the induction of a negative regulator, G10BP, which binds to three G-rich sequences in the promoter (T. Nakamura, T. Nakajima, S. Tsunoda, S....
Topics
- Adenovirus E1A Proteins
- Animals
- Base Sequence
- Cell Line, Transformed
- DNA, Single-Stranded
- Fibroblasts
- Fibronectins
- Gene Expression Regulation
- HeLa Cells
- Humans
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Promoter Regions, Genetic
- Rats
- Rats, Inbred F344
- Recombinant Fusion Proteins
- Repressor Proteins