Article
Transcriptional and posttranscriptional regulation of the proliferating cell nuclear antigen gene.
Molecular and cellular biology - 1 Jul 1990
Chang C D, Ottavio L, Travali S, Lipson K E, Baserga R
Abstract excerpt
The steady-state mRNA levels of the proliferating cell nuclear antigen (PCNA) gene are growth regulated. In a previous paper (L. Ottavio, C.-D. Chang, M. G. Rizzo, S. Travali, C. Casadevall, and R. Baserga, Mol. Cell. Biol. 10:303-309, 1990), we reported that introns (especially intron 4) participate in growth regulation of the PCNA gene. We have now investigated the role of the 5'-flanking sequence of the human...
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