Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential in vitro transcription from the promoter of a rat alpha 2u globulin gene in liver and spleen nuclear extracts.

Molecular biology & medicine - 1 Apr 1990

Sierra F, Tamone F, Mueller C R, Schibler U

Abstract excerpt

When used in an in vitro transcription assay, the promoter of a cloned alpha 2u globulin gene is much more active in liver than in spleen nuclear extracts. Promoter deletion experiments suggest that both positive and negative regulatory mechanisms may be involved in the differential in vitro transcription from the alpha 2u globulin promoter in these two nuclear extracts. Interestingly, removal of promoter...

Topics

Alpha-Globulins
Animals
Base Sequence
Cell Nucleus
Female
In Vitro Techniques
Liver
Male
Molecular Sequence Data
Mutation
Peptide Mapping
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Rats, Inbred Strains

Spleen

Templates, Genetic

Transcription, Genetic

Source

Identifiers

PMID: 1692951

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1692951-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential in vitro transcription from the promoter of a rat alpha 2u globulin gene in liver and spleen nuclear extracts.PMID 1692951Read ↗

Human sex hormone-binding globulin promoter activity is influenced by a (TAAAA)n repeat element within an Alu sequence.Semantic proximity Read ↗

Factors interacting with the rat carbamyl phosphate synthetase promoter in expressing and nonexpressing tissues.Semantic proximity Read ↗

Positive and negative regulation of the minute virus of mice P38 promoter.Semantic proximity Read ↗

Transcriptional regulation of the rat fatty acid synthase gene: identification and functional analysis of positive and negative effectors of basal transcription.Semantic proximity Read ↗

Brain-specific enhancement of the mouse neurofilament heavy gene promoter in vitro.Semantic proximity Read ↗

Genomic organization and characterization of the promoter for the E2A gene.Semantic proximity Read ↗

Structure and in vitro transcription of the rat CYP2A1 and CYP2A2 genes and regional localization of the CYP2A gene subfamily on mouse chromosome 7.Semantic proximity Read ↗

cis-Acting Elements and Transcription Factors Involved in the Promoter Activity of the Human Factor VIII GeneSemantic proximity Read ↗

In vitro activation of the mouse mid-sized neurofilament gene by an NF-1-like transcription factor.Semantic proximity Read ↗

Transcriptional analysis of the human ornithine aminotransferase promoter.Semantic proximity Read ↗

Characterization of an up-stream promoter directing extrapituitary expression of the human prolactin gene.Semantic proximity Read ↗

Negative and positive cis-acting elements control the expression of murine alpha 1-protease inhibitor genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.