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Article

cis-Acting Elements and Transcription Factors Involved in the Promoter Activity of the Human Factor VIII Gene

1 May 1995

Abstract excerpt

Factor VIII is a glycoprotein that is essential for blood coagulation. Although factor VIII mRNA has been detected in a variety of human tissues, hepatocytes are considered to be the major source of plasma factor VIII. In this report we demonstrate that the 5'-flanking region of the factor VIII gene is able to transcribe a luciferase reporter gene in three human liver-derived cell lines: PLC/PRF/5, Chang, and...

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Identifiers

PMID: 7744832
DOI: 10.1074/jbc.270.20.11828

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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