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Article

Induction of neoplastic progression in Syrian hamster embryo cells treated with protein phosphatase inhibitors.

Cancer research - 15 Apr 1993

Afshari C A, Kodama S, Bivins H M, Willard T B, Fujiki H, Barrett J C

Abstract excerpt

In these studies, Syrian hamster embryo cells (SHE), which were isolated at different stages of neoplastic progression, were used to test the ability of the protein phosphatase inhibitors, okadaic acid and sodium orthovanadate (Na3VO4) to induce neoplastic progression. We observed that these chemicals can induce transition of the cells from one stage to the other at different points in the multistep process of...

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PMID: 8385570

Genes

SHE

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