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Article

Sequential molecular and cellular events during neoplastic progression: a mouse syngeneic ovarian cancer model.

Neoplasia (New York, N.Y.) - 1 Oct 2005

Roberts Paul C, Mottillo Emilio P, Baxa Andrea C, Heng Henry H Q, Doyon-Reale Nicole, Gregoire Lucie, Lancaster Wayne D, Rabah Raja, Schmelz Eva M

Abstract excerpt

Studies performed to identify early events of ovarian cancer and to establish molecular markers to support of early detection and the development of chemopreventive regimens have been hindered by a lack of adequate cell models. Taking advantage of the spontaneous transformation of mouse ovarian surface epithelial (MOSE) cells in culture, we isolated and characterized distinct transitional stages of ovarian cancer...

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Identifiers

PMID: 16242077
DOI: 10.1593/neo.05358
PMCID: PMC1502030

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Source receipt: pubmed, retrieved 7 Sept 2026.

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