Absence of mutation in the p53 and the retinoblastoma susceptibility genes in primary cervical carcinomas.

doi:10.1006/viro.1993.1224

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Article

Absence of mutation in the p53 and the retinoblastoma susceptibility genes in primary cervical carcinomas.

Virology - 1 Apr 1993

Choo K B, Chong K Y

Abstract excerpt

Previous biochemical and structural studies using established cell lines have led to a hypothesis that the cellular p53 and the retinoblastoma susceptibility (Rb) proteins may play a crucial role in the pathogenesis process of cervical carcinoma. To further test this hypothesis, we have analyzed...

Topics

Base Sequence
Blotting, Southern
China
DNA, Neoplasm
Female
Genes, Retinoblastoma
Genes, p53
Humans
Introns
Molecular Sequence Data
Mutation
Papillomaviridae
Polymerase Chain Reaction
Sequence Deletion
Taiwan
Tumor Cells, Cultured
Uterine Cervical Neoplasms

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