Article
Absence of mutation in the p53 and the retinoblastoma susceptibility genes in primary cervical carcinomas.
Virology - 1 Apr 1993
Choo K B, Chong K Y
Abstract excerpt
Previous biochemical and structural studies using established cell lines have led to a hypothesis that the cellular p53 and the retinoblastoma susceptibility (Rb) proteins may play a crucial role in the pathogenesis process of cervical carcinoma. To further test this hypothesis, we have analyzed the structure of the p53 and Rb genes in 38 primary cervical carcinoma samples with known HPV status using the...
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