Sequence variation in the large envelope glycoprotein (E2/NS1) of hepatitis C virus during chronic infection.

doi:10.1093/infdis/167.3.726

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Article

Sequence variation in the large envelope glycoprotein (E2/NS1) of hepatitis C virus during chronic infection.

The Journal of infectious diseases - 1 Mar 1993

Kumar U, Brown J, Monjardino J, Thomas H C

Abstract excerpt

Sequence variation in the putative large surface glycoprotein (E2/NS1) of hepatitis C virus (HCV) was analyzed over 18 months in 4 patients with chronic relapsing non-A, non-B liver disease, of whom 2 were treated with lymphoblastoid interferon-alpha. Sequence analysis showed marked heterogeneity...

Topics

Adult
Amino Acid Sequence
Aspartate Aminotransferases
Base Sequence
Chronic Disease
Female
Genes, env
Genetic Variation
Hepacivirus
Hepatitis C
Humans
Interferon-gamma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Membrane Glycoproteins

Middle Aged

Molecular Sequence Data

Polymerase Chain Reaction

Sequence Homology, Amino Acid

Source

Open in PubMed

Identifiers

PMID: 8382721
DOI: 10.1093/infdis/167.3.726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8382721-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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