Article
Sequence variation in the large envelope glycoprotein (E2/NS1) of hepatitis C virus during chronic infection.
The Journal of infectious diseases - 1 Mar 1993
Kumar U, Brown J, Monjardino J, Thomas H C
Abstract excerpt
Sequence variation in the putative large surface glycoprotein (E2/NS1) of hepatitis C virus (HCV) was analyzed over 18 months in 4 patients with chronic relapsing non-A, non-B liver disease, of whom 2 were treated with lymphoblastoid interferon-alpha. Sequence analysis showed marked heterogeneity between isolates from different patients at the hypervariable region mapping to the amino-terminus of E2/NS1 (amino...
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