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Article

Evidence for a human IgG1 class switch program.

European journal of immunology - 1 Feb 1993

Irsch J, Hendriks R, Tesch H, Schuurman R, Radbruch A

Abstract excerpt

In activated murine B lymphocytes, immunoglobulin class switch recombination occurs as a highly regulated process which is targeted to distinct switch regions. Here we present first evidence that in human B lymphocytes, switch recombination is targeted to distinct switch regions as well. In a panel of clonally unrelated IgG1-expressing human B cells, immortalized by Epstein-Barr virus (EBV) transformation, seven...

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Source

Identifiers

PMID: 8382164
DOI: 10.1002/eji.1830230227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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