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Article

IgA subclass switch recombination in human mucosal and systemic immune compartments.

Mucosal immunology - 1 May 2014

Lin M, Du L, Brandtzaeg P, Pan-Hammarström Q

Abstract excerpt

Human immunoglobulin A (IgA) comprises two IgA subclasses, IgA1 and IgA2, whose distribution has been shown by immunohistochemistry to be different in various body compartments. In comparison with systemic immune compartments, we investigated the IgA switch profiles at the molecular level in salivary and lacrimal glands, nasal mucosa, and proximal and distal gut mucosa. Direct switching from IgM to IgA1 or IgA2...

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Identifiers

PMID: 24064668
DOI: 10.1038/mi.2013.68

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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