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Article

Targeting of human switch recombination breakpoints: implications for the mechanism of mu-gamma isotype switching.

European journal of immunology - 1 Sept 1999

Pan Q, Hammarström L

Abstract excerpt

We recently characterized the allelic variants of the human Sgamma4 region which makes it possible to accurately identity and map Smu-Sgamma4 fragments from in vivo switched B cells. Twenty-six fragments were identified and a comparison was made with all previously published Smu-Sgamma sequences ( n = 82). Switch recombination outside the region flanking the Sgamma repeat sequence is a rare event in vivo and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulin Class Switching

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Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 10508252
DOI: 10.1002/(SICI)1521-4141(199909)29:09<2779::AID-IMMU2779>3.0.CO;2-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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