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Article

Switch recombination in normal IgA1+ B lymphocytes.

Proceedings of the National Academy of Sciences of the United States of America - 15 Feb 1994

Irsch J, Irlenbusch S, Radl J, Burrows P D, Cooper M D, Radbruch A H

Abstract excerpt

Most B lymphocytes in normal individuals express two classes of cell-surface immunoglobulins, IgM and IgD. The specificity of the two antigen receptors is identical since they are produced by transcription and differential splicing of the same variable region gene segment to the heavy-chain constant region gene segments for both mu and delta heavy chains. B lymphocytes expressing other immunoglobulin isotypes,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8108410
DOI: 10.1073/pnas.91.4.1323
PMCID: PMC43150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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