Article
Antigen recognition properties of mutant V beta 3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor.
The Journal of experimental medicine - 1 Jan 1993
White J, Pullen A, Choi K, Marrack P, Kappler J W
Abstract excerpt
We examined the effect of mutations in the V beta portion of a pigeon cytochrome c (cyto c)-specific V beta 3+/V alpha 11+ T cell receptor on its ability to recognize cyto c/IEk and various superantigens. The results were consistent with an immunoglobulin-like structure for the receptor V beta do...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Columbidae
- Cytochrome c Group
- Histocompatibility Antigens Class II
- Immunoglobulin Variable Region
- Mice
- Molecular Sequence Data
- Mutation
- Receptors, Antigen, T-Cell, alpha-beta
- Structure-Activity Relationship