Article
Molecular characterization of the putative T-cell receptor cavity of the superantigen staphylococcal enterotoxin B.
Immunology - 1 Jun 1998
Garcia C, Briggs C, Zhang L, Guan L, Gabriel J L, Rogers T J
Abstract excerpt
A number of investigators have utilized a variety of methods to identify the structural basis for the interaction of superantigens with the T-cell receptor beta-chain. The previous studies strongly suggest that a region of the toxin near residues N23, Y61, Y91 and D209 is important for this binding activity. Examination of crystal structure data shows that these residues line the rim of one side of a shallow...
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